The Lake County Major Crash Assistance Team (MCAT) investigates a head-on crash caused by a wrong-way driver that left one person dead and another seriously injured on Route 41 south of Route 176 in Lake Bluff early Sunday morning. | Photo: Max Weingardt

One person has died and a second person was seriously injured after a wrong-way driver crashed head-on into another vehicle on Route 41 in Lake Bluff Sunday morning.

The Lake Bluff Police Department, Lake Forest Fire Department and Lake Bluff Fire Department responded around 4:52 a.m. to Route 41 south of Route 176 for a report of a vehicle crash with injuries.

Lake Bluff Deputy Police Chief Erik Gehrke said officers arrived to find two vehicles were involved in a front-end collision.

The Lake County Major Crash Assistance Team (MCAT) investigates a head-on crash caused by a wrong-way driver that left a 20-year-old woman dead and another person seriously injured on Route 41 south of Route 176 in Lake Bluff early Sunday morning. | Photo: Max Weingardt

A preliminary investigation showed one of the two vehicles was traveling southbound in the northbound lanes of Route 41, resulting in the head-on crash.

The Lake Forest Fire Department responded with two ambulances to the scene.

One driver was determined to be deceased at the scene while the other driver was transported to an area hospital with “significant injuries,” Gehrke said.

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The drivers were the sole occupants of their vehicles and no other passengers were found.

Police shut down the northbound lanes of Route 41 between Route 60 and Route 176 in Lake Forest and Lake Bluff after a head-on crash caused by a wrong-way driver left one person dead and another seriously injured early Sunday morning. | Photo: Max Weingardt

The Lake Bluff Police Department requested assistance from the Lake County Major Crash Assistance Team (MCAT) to aid in the investigation due to the severity of the crash.

Northbound Route 41 was shut down at Route 60 and remained closed until around 9:45 a.m. when the scene investigation was completed and the cars were removed.

Gehrke said the people involved in the crash have yet to be identified and further information on the incident would be released as it becomes available.